p73 keeps metabolic control in balance

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p73 keeps metabolic control in balance

Comment on: Velletri T, et al. Cell Cycle 2013; 12:3564–73; PMID:24121663; http://dx.doi.org/10.4161/cc.26771 Francesca Cutruzzolà, Luciana Avigliano, and Eleonora Candi*; Sapienza University of Rome; Department of Biochemistry “A. Rossi Fanelli”; Rome, Italy; University of Tor Vergata; Department of Experimental Medicine and Surgery; Rome, Italy; *Email: [email protected]; http://dx.doi.org/10...

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Role of p73 Dinucleotide Polymorphism in Prostate Cancer and p73 Protein Isoform Balance

Background. Molecular markers for prostate cancer (PCa) risks are currently lacking. Here we address the potential association of a dinucleotide polymorphism (DNP) in exon 2 of the p73 gene with PCa risk/progression and discern any disruption of p73 protein isoforms levels in cells harboring a p73 DNP allele. Methods. We investigated the association between p73 DNP genotype and PCa risk/aggress...

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ژورنال

عنوان ژورنال: Cell Cycle

سال: 2013

ISSN: 1538-4101,1551-4005

DOI: 10.4161/cc.27301